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Receptor

Search Result - 1

HMRbase accession number	20052
Swiss-prot Accession number	O18821 (Sequence in FASTA format)
Description	Gonadotropin-releasing hormone receptor (GnRH receptor) (GnRH-R).
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for gonadotropin releasing hormone (GnRH) that mediate the action of GnRH to stimulate the secretion of the gonadotropic hormones (LH and FSH). This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity).
Protein Length	328 Amino acids
Molecular weight	37649
Domain Name	7tm_1
References	1   Porter M.B., Green M.L., Simmen R.C.M., Sharp D.C.; "Cloning and sequencing of the equine pituitary gonadotropin-releasinghormone receptor and expression of its mRNA following administrationof pulsatile or continuous GnRH."; Submitted (JUN-2000) to the EMBL/GenBank/DDBJ databases.
Hormone	N/A
Gene ID	100033874
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 2

HMRbase accession number	20912
Swiss-prot Accession number	P79166 (Sequence in FASTA format)
Description	Melanocyte-stimulating hormone receptor (MSH-R) (Melanotropinreceptor) (Melanocortin receptor 1) (MC1-R).
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Receptor for MSH (alpha, beta) and ACTH. Does not seem to be active with gamma-MSH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase.
Protein Length	317 Amino acids
Molecular weight	35213
Domain Name	7tm_1
References	1  PubMed abstract 11353392 2  PubMed abstract 8995760 3  PubMed abstract 11353392 4  PubMed abstract 8995760
Hormone	N/A
Gene ID	100136907
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 3

HMRbase accession number	21046
Swiss-prot Accession number	P47799 (Sequence in FASTA format)
Description	Follicle-stimulating hormone receptor precursor (FSH-R) (Follitropinreceptor).
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	Membrane; multi-pass membrane protein
Developmental Stage	N/A
Similarity	Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. Contains 10 LRR (leucine-rich) repeats.
Tissue Specificity	N/A
Post translational modification	N-glycosylated; indirectly required for FSH-binding, possibly via a conformational change that allows high affinity binding of hormone (By similarity).
Function	Receptor for follicle-stimulating hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Among all mammalian FSH receptors, on the horse receptor does not bind LH/chorionic gonadotrophin (CG).
Protein Length	694 Amino acids
Molecular weight	78005
Domain Name	N/A
References	1  PubMed abstract 8198575 2  PubMed abstract 8198575
Hormone	P01220   Detail in HMRbase    P01226   Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 4

HMRbase accession number	21255
Swiss-prot Accession number	Q9TV98 (Sequence in FASTA format)
Description	RecName: Estrogen receptor;ER;Alternative Name: Estradiol receptor;Alternative Name: ER-alpha;Alternative Name: Nuclear receptor subfamily 3 group A member 1;
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	Nucleus (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues (By similarity).
Protein Length	594 Amino acids
Molecular weight	66104
Domain Name	Hormone_recep  Oest_recep  zf-C4
References	----
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	791249
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 5

HMRbase accession number	21494
Swiss-prot Accession number	Q9GKL2 (Sequence in FASTA format)
Description	Steroidogenic factor 1;STF-1;SF-1;Alternative Name: Nuclear receptor subfamily 5 group A member 1
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	Nucleus (By similarity)
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. NR5 subfamily. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	Acetylation stimulates the transcriptional activity (By similarity).
Function	Transcriptional activator. Seems to be essential for sexual differentiation and formation of the primary steroidogenic tissues. Binds to the Ad4 site found in the promoter region of steroidogenic P-450 genes such as CYP11A, CYP11B and CYP21B. Also regulates the Muellerian inhibiting substance (AMH) gene as well as the AHCH and STAR genes. 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' are the consensus sequences for the recognition by NR5A1/FTZF1. The SFPQ-NONO-NR5A1/SF-1 complex binds to the CYP17 promoter and regulates basal and cAMP-dependent transcriptional avtivity. Binds phospholipids with a phosphatidylinositol (PI) headgroup, in particular PI(3,4)P2 and PI(3,4,5)P3 (By similarity).
Protein Length	461 Amino acids
Molecular weight	51644
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 11108279
Hormone	N/A
Gene ID	100033902
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 6

HMRbase accession number	21769
Swiss-prot Accession number	O19008 (Sequence in FASTA format)
Description	Progesterone receptor; Fragment
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	118 Amino acids
Molecular weight	13857
Domain Name	Hormone_recep
References	1  PubMed abstract 9763674
Hormone	Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 7

HMRbase accession number	21770
Swiss-prot Accession number	O19009 (Sequence in FASTA format)
Description	Estrogen receptor alpha; Fragment
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	125 Amino acids
Molecular weight	14309
Domain Name	Hormone_recep
References	1  PubMed abstract 9763674
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 8

HMRbase accession number	21880
Swiss-prot Accession number	O62758 (Sequence in FASTA format)
Description	Progesterone receptor; Fragment
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	208 Amino acids
Molecular weight	21084
Domain Name	Prog_receptor
References	----
Hormone	Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 9

HMRbase accession number	22198
Swiss-prot Accession number	Q6TN19 (Sequence in FASTA format)
Description	Glucocorticoid receptor; Fragment
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	114 Amino acids
Molecular weight	12457
Domain Name	GCR
References	----
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 10

HMRbase accession number	22468
Swiss-prot Accession number	Q8MJ07 (Sequence in FASTA format)
Description	Androgen receptor; Fragment
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	212 Amino acids
Molecular weight	23533
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 15223842
Hormone	Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase    Detail in HMRbase
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments

Search Result - 11

HMRbase accession number	22510
Swiss-prot Accession number	Q8SPK8 (Sequence in FASTA format)
Description	Estradiol receptor beta; Fragment
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	87 Amino acids
Molecular weight	10155
Domain Name	Hormone_recep
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 12

HMRbase accession number	22736
Swiss-prot Accession number	Q9GKL1 (Sequence in FASTA format)
Description	Steroidogenic factor 2
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	Belongs to the nuclear hormone receptor family. Contains 1 nuclear receptor DNA-binding domain.
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	495 Amino acids
Molecular weight	56443
Domain Name	Hormone_recep  zf-C4
References	1  PubMed abstract 11108279
Hormone	N/A
Gene ID	100009700
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 13

HMRbase accession number	22815
Swiss-prot Accession number	Q9MZS0 (Sequence in FASTA format)
Description	Steroidogenic factor-1; Fragment
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	181 Amino acids
Molecular weight	19313
Domain Name	N/A
References	1  PubMed abstract 11108279
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated

Search Result - 14

HMRbase accession number	22816
Swiss-prot Accession number	Q9MZS3 (Sequence in FASTA format)
Description	Orphan nuclear receptor DAX-1; Fragment
Source organism	Equus caballus (Horse)
Taxonomical Classification	Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
Subcellular location	N/A
Developmental Stage	N/A
Similarity	N/A
Tissue Specificity	N/A
Post translational modification	N/A
Function	N/A
Protein Length	320 Amino acids
Molecular weight	35834
Domain Name	Hormone_recep
References	----
Hormone	N/A
Gene ID	N/A
PDB ID	N/A
Drugpedia	wiki
Comments	!Hormone for this Receptor are either unknown or have not yet been curated